Therefore, results here discussed indicate that PFS is an emerging clinical problem that needs to be further elucidated. 2015;104:107. WebA deterioration in the quality of life in affected individuals does not justify use of the drug. .s5ap8yh1b4ZfwxvHizW3f{color:var(--newCommunityTheme-metaText);padding-top:5px}.s5ap8yh1b4ZfwxvHizW3f._19JhaP1slDQqu2XgT3vVS0{color:#ea0027} 2023 by The President and Fellows of Harvard College, Do not sell my personal information | Privacy Policy. Do you and your partner want to have a baby? When did you first begin having dry orgasms? | How To Diagnose And Reverse It. Of course I said this in a respectable manner Result: post deleted and banned. The number of men sharing their experience of Post-Finasteride Syndrome is steadily rising, painting a bleak picture of the life-shattering effects the drug can have. Advertising revenue supports our not-for-profit mission. On a sidenote i've seen a few other people recover the same way. If we cant discuss potential cures then that forum is completely worthless and I start to doubt their real intentions. Better to learn the cause of PFS and create a cure based on that. Adverse effects of 5-reductase inhibitors: What do we know, don't know, and need to know? breast tenderness. https://old.reddit.com/r/FinasterideSyndrome/comments/psjeuu/could_trying_finasteride_for_1_month_be_harmfull/he38hlf/. What was the article? Anejaculation and retrograde ejaculation. Maybe if theyre lucky in 10 years. Brain Res Bull. | How To Diagnose And Reverse It. The common denominator in how I feel is Tribulus, period, end of sentence. Day 2 I noticed a bit more energy, but credited that to having a good night's sleep (did I mention this stuff helps you sleep better, too?) .Rd5g7JmL4Fdk-aZi1-U_V{transition:all .1s linear 0s}._2TMXtA984ePtHXMkOpHNQm{font-size:16px;font-weight:500;line-height:20px;margin-bottom:4px}.CneW1mCG4WJXxJbZl5tzH{border-top:1px solid var(--newRedditTheme-line);margin-top:16px;padding-top:16px}._11ARF4IQO4h3HeKPpPg0xb{transition:all .1s linear 0s;display:none;fill:var(--newCommunityTheme-button);height:16px;width:16px;vertical-align:middle;margin-bottom:2px;margin-left:4px;cursor:pointer}._1I3N-uBrbZH-ywcmCnwv_B:hover ._11ARF4IQO4h3HeKPpPg0xb{display:inline-block}._2IvhQwkgv_7K0Q3R0695Cs{border-radius:4px;border:1px solid var(--newCommunityTheme-line)}._2IvhQwkgv_7K0Q3R0695Cs:focus{outline:none}._1I3N-uBrbZH-ywcmCnwv_B{transition:all .1s linear 0s;border-radius:4px;border:1px solid var(--newCommunityTheme-line)}._1I3N-uBrbZH-ywcmCnwv_B:focus{outline:none}._1I3N-uBrbZH-ywcmCnwv_B.IeceazVNz_gGZfKXub0ak,._1I3N-uBrbZH-ywcmCnwv_B:hover{border:1px solid var(--newCommunityTheme-button)}._35hmSCjPO8OEezK36eUXpk._35hmSCjPO8OEezK36eUXpk._35hmSCjPO8OEezK36eUXpk{margin-top:25px;left:-9px}._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP,._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP:focus-within,._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP:hover{transition:all .1s linear 0s;border:none;padding:8px 8px 0}._25yWxLGH4C6j26OKFx8kD5{display:inline}._2YsVWIEj0doZMxreeY6iDG{font-size:12px;font-weight:400;line-height:16px;color:var(--newCommunityTheme-metaText);display:-ms-flexbox;display:flex;padding:4px 6px}._1hFCAcL4_gkyWN0KM96zgg{color:var(--newCommunityTheme-button);margin-right:8px;margin-left:auto;color:var(--newCommunityTheme-errorText)}._1hFCAcL4_gkyWN0KM96zgg,._1dF0IdghIrnqkJiUxfswxd{font-size:12px;font-weight:700;line-height:16px;cursor:pointer;-ms-flex-item-align:end;align-self:flex-end;-webkit-user-select:none;-ms-user-select:none;user-select:none}._1dF0IdghIrnqkJiUxfswxd{color:var(--newCommunityTheme-button)}._3VGrhUu842I3acqBMCoSAq{font-weight:700;color:#ff4500;text-transform:uppercase;margin-right:4px}._3VGrhUu842I3acqBMCoSAq,.edyFgPHILhf5OLH2vk-tk{font-size:12px;line-height:16px}.edyFgPHILhf5OLH2vk-tk{font-weight:400;-ms-flex-preferred-size:100%;flex-basis:100%;margin-bottom:4px;color:var(--newCommunityTheme-metaText)}._19lMIGqzfTPVY3ssqTiZSX._19lMIGqzfTPVY3ssqTiZSX._19lMIGqzfTPVY3ssqTiZSX{margin-top:6px}._19lMIGqzfTPVY3ssqTiZSX._19lMIGqzfTPVY3ssqTiZSX._19lMIGqzfTPVY3ssqTiZSX._3MAHaXXXXi9Xrmc_oMPTdP{margin-top:4px} ._1LHxa-yaHJwrPK8kuyv_Y4{width:100%}._1LHxa-yaHJwrPK8kuyv_Y4:hover ._31L3r0EWsU0weoMZvEJcUA{display:none}._1LHxa-yaHJwrPK8kuyv_Y4 ._31L3r0EWsU0weoMZvEJcUA,._1LHxa-yaHJwrPK8kuyv_Y4:hover ._11Zy7Yp4S1ZArNqhUQ0jZW{display:block}._1LHxa-yaHJwrPK8kuyv_Y4 ._11Zy7Yp4S1ZArNqhUQ0jZW{display:none} What Causes Hair Loss in Women? Press question mark to learn the rest of the keyboard shortcuts. I had a case of PFS that was a severe as it gets. I understand not wanting to have a bunch of hack cures on their forum that dont really do anything or worse yet, make people worse, but at some point when theres a condition we dont know how to fix it seems like some trial and error wouldnt be the worst idea in the world. Tamoxifen I did 20mg during the four weeks every day. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. Are there other possible causes for my symptoms or condition? To give you a bit of background, I'm a 34 year old male whose sexual function was utterly destroyed by finasteride/Propecia. Chlorpheniramine and brompheniramine, antihistamines that help relieve allergies. As a 5-alpha reductase inhibitor, finasteride works by inhibiting the effects of the enzyme thats responsible for converting testosterone into dihydrotestosterone (DHT). As here reported, these observations are mainly based on self-reporting of the symptomatology by the patients and few clinical studies have been performed so far. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). The data does support that finasteride does have sexual side-effects for guys that are not on TRT while you are using it. In addition, molecular mechanisms and/or genetic determinants behind such adverse effects have been poorly explored both in patients and animal models. As a service to our readers, Harvard Health Publishing provides access to our library of archived content. I did the first day 300 mg clomid, then 100mg for the first two weeks, 50mg for the third week, and none for the forth week. To be honest, I think for the most part these recoveries werent PFS but rather hormonal imbalances. WebI cannot say enough about this. You are spreading nonsense, people have been trying that crap for years to no effect. Midodrine, a medicine that constricts blood vessels. What is likely causing my symptoms or condition? 2022 Jul 27;15(8):930. doi: 10.3390/ph15080930. https://forum.propeciahelp.com/t/joekool-s-story-long-term-hcg/46717. Plentiful in opinions, short on facts. A single copy of these materials may be reprinted for noncommercial personal use only. ._9ZuQyDXhFth1qKJF4KNm8{padding:12px 12px 40px}._2iNJX36LR2tMHx_unzEkVM,._1JmnMJclrTwTPpAip5U_Hm{font-size:16px;font-weight:500;line-height:20px;color:var(--newCommunityTheme-bodyText);margin-bottom:40px;padding-top:4px;text-align:left;margin-right:28px}._2iNJX36LR2tMHx_unzEkVM{-ms-flex-align:center;align-items:center;display:-ms-flexbox;display:flex}._2iNJX36LR2tMHx_unzEkVM ._24r4TaTKqNLBGA3VgswFrN{margin-left:6px}._306gA2lxjCHX44ssikUp3O{margin-bottom:32px}._1Omf6afKRpv3RKNCWjIyJ4{font-size:18px;font-weight:500;line-height:22px;border-bottom:2px solid var(--newCommunityTheme-line);color:var(--newCommunityTheme-bodyText);margin-bottom:8px;padding-bottom:8px}._2Ss7VGMX-UPKt9NhFRtgTz{margin-bottom:24px}._3vWu4F9B4X4Yc-Gm86-FMP{border-bottom:1px solid var(--newCommunityTheme-line);margin-bottom:8px;padding-bottom:2px}._3vWu4F9B4X4Yc-Gm86-FMP:last-of-type{border-bottom-width:0}._2qAEe8HGjtHsuKsHqNCa9u{font-size:14px;font-weight:500;line-height:18px;color:var(--newCommunityTheme-bodyText);padding-bottom:8px;padding-top:8px}.c5RWd-O3CYE-XSLdTyjtI{padding:8px 0}._3whORKuQps-WQpSceAyHuF{font-size:12px;font-weight:400;line-height:16px;color:var(--newCommunityTheme-actionIcon);margin-bottom:8px}._1Qk-ka6_CJz1fU3OUfeznu{margin-bottom:8px}._3ds8Wk2l32hr3hLddQshhG{font-weight:500}._1h0r6vtgOzgWtu-GNBO6Yb,._3ds8Wk2l32hr3hLddQshhG{font-size:12px;line-height:16px;color:var(--newCommunityTheme-actionIcon)}._1h0r6vtgOzgWtu-GNBO6Yb{font-weight:400}.horIoLCod23xkzt7MmTpC{font-size:12px;font-weight:400;line-height:16px;color:#ea0027}._33Iw1wpNZ-uhC05tWsB9xi{margin-top:24px}._2M7LQbQxH40ingJ9h9RslL{font-size:12px;font-weight:400;line-height:16px;color:var(--newCommunityTheme-actionIcon);margin-bottom:8px} Last time I was on there they had started discussing some relationships between HCG and Thyroid? I had all the classic symptoms. Can electrical brain stimulation boost attention, memory, and more? My personal experience is that finasteride is an important medication for older guys on TRT that are experiencing BPH. I did this for 6 months straight but at the 10th week or so, the improvements were weekly. I suspect its because my E2 was so low already and that made it feel even lower (single digits if I recall correctly). Ketamine for treatment-resistant depression: When and where is it safe? Fertility and Sterility. My hair loss is back full force, but so is my libido and so are my erections. Best, Dr. Emer. I also tried testosterone treatment but it had almost no effect regardless of dosage. 5alpha-reductase; Androgenetic alopecia; Depression; Finasteride; Neuroactive steroids; Sexual dysfunction. Proviron saved my life. I took 2 capsules before my daily workout at around 6pm and another 4 capsules 20 minutes before bedtime. For details, see text. 2021 Dec 13;54(4):422-434. doi: 10.1055/s-0041-1739254. Mesterolone (Proviron) is one of the best compounds that can be used for treating Post Finasteride Syndrome in my opinion. And yeah I know hackstasis, looks to be a much better community and forum than propeciahelp without fascist mods. An official website of the United States government. government site. Neuroactive steroid levels are modified in cerebrospinal fluid and plasma of post-finasteride patients showing persistent sexual side effects and anxious/depressive symptomatology. ._2ik4YxCeEmPotQkDrf9tT5{width:100%}._1DR1r7cWVoK2RVj_pKKyPF,._2ik4YxCeEmPotQkDrf9tT5{display:-ms-flexbox;display:flex;-ms-flex-align:center;align-items:center}._1DR1r7cWVoK2RVj_pKKyPF{-ms-flex-pack:center;justify-content:center;max-width:100%}._1CVe5UNoFFPNZQdcj1E7qb{-ms-flex-negative:0;flex-shrink:0;margin-right:4px}._2UOVKq8AASb4UjcU1wrCil{height:28px;width:28px;margin-top:6px}.FB0XngPKpgt3Ui354TbYQ{display:-ms-flexbox;display:flex;-ms-flex-align:start;align-items:flex-start;-ms-flex-direction:column;flex-direction:column;margin-left:8px;min-width:0}._3tIyrJzJQoNhuwDSYG5PGy{display:-ms-flexbox;display:flex;-ms-flex-align:center;align-items:center;width:100%}.TIveY2GD5UQpMI7hBO69I{font-size:12px;font-weight:500;line-height:16px;color:var(--newRedditTheme-titleText);white-space:nowrap;overflow:hidden;text-overflow:ellipsis}.e9ybGKB-qvCqbOOAHfFpF{display:-ms-flexbox;display:flex;-ms-flex-align:center;align-items:center;width:100%;max-width:100%;margin-top:2px}.y3jF8D--GYQUXbjpSOL5.y3jF8D--GYQUXbjpSOL5{font-weight:400;box-sizing:border-box}._28u73JpPTG4y_Vu5Qute7n{margin-left:4px} Don't listen to bad doctors who tell you its all in your head. However, minoxidil is used "off-label" for treating telogen effluvium, scarring alopecia and alopecia areata. Getting to the root cause of your hairloss would be the first thing to do as if you have an underlying medical condition, once thats treated, it could reverse the hairloss, so definately get a consultation with a physician to rule out anything treatable. Teeranachaideekul V, Parichatikanond W, Junyaprasert VB, Morakul B. 2015;12:401. This type of damage can be caused by diabetes, multiple sclerosis, certain surgeries, and other conditions and treatments. The .gov means its official. After numerous labs, I have determined that a dose of 2-3 mg is optimal for keeping my DHT within the normal range. HHS Vulnerability Disclosure, Help The results have been amazing and far too great to chalk it up to just being a placebo. In this review, we focused our attention on adverse events related to 5 alpha-reductase (5-R) inhibitors (i.e., finasteride and dutasteride), approved for the treatment of benign prostatic hyperplasia and androgenetic alopecia (AGA). Careers. Thats probably the worst part if you only read that forum youre pretty much going to feel hopeless. Metabolism of progesterone and testosterone, Metabolism of progesterone and testosterone into 5alpha-reduced metabolites and their mechanisms of action:, Clinical features reported in patients affected by post-finasteride syndrome. Can sperm be retrieved from my bladder and used for fertility treatment? This content does not have an Arabic version. Pharmacological Management of Pattern Hair Loss. Brain fog. Is there a generic alternative to the medicine you're prescribing me? https://old.reddit.com/r/steroids/comments/m5m7o9/help_steroids_for_pssd/gr0uhqj/. Almost starting to think like a conspiracy theorist. I feel like I have my life back. Epub 2022 Feb 3. Male pattern baldness develops when DHT binds to receptors in the scalp and causes the hair follicles to miniaturize. Gut Inflammation Induced by Finasteride Withdrawal: Therapeutic Effect of Allopregnanolone in Adult Male Rats. Pharmaceuticals (Basel). Or at the very least allow people to post ideas. The information on RealSelf is intended for educational purposes only. Im only able to maintain arousal under very peculiar circumstances, and even thats not the level of hardness Im used to having pre-fin. Traish AM, Melcangi RC, Bortolato M, Garcia-Segura LM, Zitzmann M. Rev Endocr Metab Disord. The site is secure. Disclaimer. Do a physical exam, which will likely include an exam of your penis, testicles and rectum. If I do achieve an erection it has to be constantly stimulated or it goes away FAST and even thats not a guarantee. Metab. Therefore, I cut the pills in half (2.5mg) and toss the other half. Retrograde ejaculation typically doesn't require treatment unless it interferes with fertility. I'm not going to go into the entire history of what post finasteride syndrome is, and I assume many of you looking into buying Tribulus know exactly what it is. 2018;120:143149. I am not aware of the use of Human Growth Hormone in the treatment for Post Finasteride Syndrome. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book: Mayo Clinic Family Health Book, 5th Edition, Book: Mayo Clinic Guide to Fertility and Conception. When seeing your doctor for dry ejaculation the primary sign of retrograde ejaculation some basic questions to ask your doctor include: If you're trying to get your female partner pregnant, you might also want to ask: In addition to the questions that you've prepared to ask your doctor, don't hesitate to ask additional questions during your appointment. "I had a case of PFS that was a severe as it gets. Int. When dosed properly, it can bring DHT within normal ranges very effectively. https://www.amazon.com/reviews/R3OGTPUQ1CP005. I did a limited search and did not find other such claims. Your doctor will ask you to empty your bladder, masturbate to climax and then provide a urine sample for laboratory analysis. FOIA ._1x9diBHPBP-hL1JiwUwJ5J{font-size:14px;font-weight:500;line-height:18px;color:#ff585b;padding-left:3px;padding-right:24px}._2B0OHMLKb9TXNdd9g5Ere-,._1xKxnscCn2PjBiXhorZef4{height:16px;padding-right:4px;vertical-align:top}.icon._1LLqoNXrOsaIkMtOuTBmO5{height:20px;vertical-align:middle;padding-right:8px}.QB2Yrr8uihZVRhvwrKuMS{height:18px;padding-right:8px;vertical-align:top}._3w_KK8BUvCMkCPWZVsZQn0{font-size:14px;font-weight:500;line-height:18px;color:var(--newCommunityTheme-actionIcon)}._3w_KK8BUvCMkCPWZVsZQn0 ._1LLqoNXrOsaIkMtOuTBmO5,._3w_KK8BUvCMkCPWZVsZQn0 ._2B0OHMLKb9TXNdd9g5Ere-,._3w_KK8BUvCMkCPWZVsZQn0 ._1xKxnscCn2PjBiXhorZef4,._3w_KK8BUvCMkCPWZVsZQn0 .QB2Yrr8uihZVRhvwrKuMS{fill:var(--newCommunityTheme-actionIcon)} That is 250IU, not a typo so youll mix your 5000iu HCG with 5CC water and take 1/4 CC intramuscular three times a week using an insulin needle Have you heard about it? WebPost finasteride syndrome is real. Indian J Plast Surg. However, some men report persistent sex drive and ejaculation problems after stopping the medication. 12th ed. Shift work can harm sleep and health: What helps? Thanks for visiting. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Now and for the past six months, I feel great, my libido is great, mental issues are gone, ED is gone. 2022 Oct;11(10):1452-1457. doi: 10.21037/tau-22-92. These hippocampal neurogenesis changes after finasteride treatment have been linked to emotional behavior and this might contribute to the pathophysiology of affective disorders in humans. I did three months on testosterone injections and muscle building. Case report: a study of the clinical characteristics and genetic variants of post-finasteride syndrome patients. Write down any symptoms you're experiencing, including any that might seem unrelated to the reason for which you scheduled the appointment. Key takeaways: Finasteride is an FDA-approved medication that treats hair loss in men. Like I said, almost starting to believe they want people to keep having pfs so they can benefit in some form or another. Their attitude is 100% there is no cure, it wont get better, nothing works, anything that does work doesnt work long term, and thats just how it is. Sexual side effects: Loss of libido, impotence, testicular pain, testicle shrinkage, minor Peyronies (up to 10 degrees), penis pain, watery semen, Mental: Anxiety, insomnia, cognitive issues / brain fog. When you are on TRT, your DHT levels tend to go out of the normal range and finasteride is a mechanism for bringing it back into range. Even Viagra wouldnt get me hard. However, careful selection of patients and monitoring the finasteride treatment may prevent the PFS to some extent. On PFS forums, peoples dicks got 1 inch bigger when erect, here and there, they sometimes felt sexual attraction towards women. Finasteride causes cognitive & sexual decline. ._1QwShihKKlyRXyQSlqYaWW{height:16px;width:16px;vertical-align:bottom}._2X6EB3ZhEeXCh1eIVA64XM{margin-left:3px}._1jNPl3YUk6zbpLWdjaJT1r{font-size:12px;font-weight:500;line-height:16px;border-radius:2px;display:inline-block;margin-right:5px;overflow:hidden;text-overflow:ellipsis;vertical-align:text-bottom;white-space:pre;word-break:normal;padding:0 4px}._1jNPl3YUk6zbpLWdjaJT1r._39BEcWjOlYi1QGcJil6-yl{padding:0}._2hSecp_zkPm_s5ddV2htoj{font-size:12px;font-weight:500;line-height:16px;border-radius:2px;display:inline-block;margin-right:5px;overflow:hidden;text-overflow:ellipsis;vertical-align:text-bottom;white-space:pre;word-break:normal;margin-left:0;padding:0 4px}._2hSecp_zkPm_s5ddV2htoj._39BEcWjOlYi1QGcJil6-yl{padding:0}._1wzhGvvafQFOWAyA157okr{font-size:12px;font-weight:500;line-height:16px;border-radius:2px;margin-right:5px;overflow:hidden;text-overflow:ellipsis;vertical-align:text-bottom;white-space:pre;word-break:normal;box-sizing:border-box;line-height:14px;padding:0 4px}._3BPVpMSn5b1vb1yTQuqCRH,._1wzhGvvafQFOWAyA157okr{display:inline-block;height:16px}._3BPVpMSn5b1vb1yTQuqCRH{background-color:var(--newRedditTheme-body);border-radius:50%;margin-left:5px;text-align:center;width:16px}._2cvySYWkqJfynvXFOpNc5L{height:10px;width:10px}.aJrgrewN9C8x1Fusdx4hh{padding:2px 8px}._1wj6zoMi6hRP5YhJ8nXWXE{font-size:14px;padding:7px 12px}._2VqfzH0dZ9dIl3XWNxs42y{border-radius:20px}._2VqfzH0dZ9dIl3XWNxs42y:hover{opacity:.85}._2VqfzH0dZ9dIl3XWNxs42y:active{transform:scale(.95)} The article stated proviron was the best potential cure in his opinion. Lol, now they banned me, just look at the reason: Dismissive of survey in first few posts; insistently advocated for dangerous and misleading article on PFS. Finasteride (Propecia) is a medication that can help treat MPB by lowering levels of DHT. Do you have diabetes or any other chronic health problems? Speaking of which the proviron I ordered over a year ago randomly came in the mail the other day, haha. Don't miss your FREE gift. -, Basaria S., Jasuja R., Huang G., Wharton W., Pan H., Pencina K., Li Z., Travison T.G., Bhawan J., Gonthier R., Labrie F., Dury A.Y., Serra C., Papazian A., O'Leary M., Amr S., Storer T.W., Stern E., Bhasin S. Characteristics of men who report persistent sexual symptoms after finasteride use for hair loss. Here's some information to help you get ready for your appointment, and what to expect from your doctor. Res. 2008;35:211. And posted the article and some cliffs about his solution. ._3Z6MIaeww5ZxzFqWHAEUxa{margin-top:8px}._3Z6MIaeww5ZxzFqWHAEUxa ._3EpRuHW1VpLFcj-lugsvP_{color:inherit}._3Z6MIaeww5ZxzFqWHAEUxa svg._31U86fGhtxsxdGmOUf3KOM{color:inherit;fill:inherit;padding-right:8px}._3Z6MIaeww5ZxzFqWHAEUxa ._2mk9m3mkUAeEGtGQLNCVsJ{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:18px;color:inherit} Eliminate Trigger Foods. Andracim Gel (small 2 eminem size, 1 on each size of rib cage, less is more with this stuff). Minoxidil is FDA approved for genetic hair loss - it does not help other conditions quite so much. Minoxidil takes 4-6 months before an individual should assess whether or not it helps. What the hell? You can't get worse than living with no dick dude. doi: 10.1210/jc.2016-2726. Personally, I believe its become the boogeyman for a bucket list of sexual problems. Next to no sensitivity in my genitals. And quite frankly, if you think big pharma doesn't have millions and millions of dollars wrapped up in trying to cover up just how severely finasteride has destroyed mens' lives, you're fooling yourself. The symptoms of PFS start to subside within four to eight months after discontinuing the medicine. His article with all the studies hes referencing: Post Finasteride Syndrome can be manually corrected by interpreting blood work and implementing an appropriate lifestyle and/or pharmacological protocol. I took a prescription-strength anti-estrogen, Tamoxifen 10mg, twice a day: one at around 3pm and another one together with my test booster before bedtime. -, Alkahtane A.A., Albasher G., Al-Sultan N.K., Alqahtani W.S., Alarifi S., Almeer R.S., Alghamdi J., Ali D., Alahmari A., Alkahtani S. Long-term treatment with finasteride induces apoptosis and pathological changes in female mice. rash. Bethesda, MD 20894, Web Policies https://forum.propeciahelp.com/t/my-story-yes-it-was-messy-and-yes-i-am-fine-now/5456. It can prevent hair loss and decrease prostate enlargement, but not surprisingly, it can also suppress sexual function. At first, I felt absolutely miserable when doing so, it is the worst Ive felt in my life and I was unable to do almost anything but after some weeks it became more tolerable as the receptors lost some of their sensitivity. If a high volume of sperm is found in your urine, you have retrograde ejaculation. And youre competely right, they make it sound like youre doomed and you shouldnt try anything but wait for the Baylor study and fill out the surveyDo they really expect some magical cure to come out when Baylor releases or their survey has enough participants? How is your dick being equivalent to your thumb not severe? Gained 25 pounds of mostly muscle. Finasteride blocks the metabolism of testosterone. If medication doesn't allow you to ejaculate semen, you will likely need infertility procedures known as assisted reproductive technology to get your partner pregnant. Midodrine, a medicine that constricts blood vessels, Chlorpheniramine and brompheniramine, antihistamines that help relieve allergies, Ephedrine, pseudoephedrine and phenylephrine, medicines that help relieve symptoms of the common cold. Feeling low-grade depression constantly. Adverse side effects of 5-reductase inhibitors therapy: persistent diminished libido and erectile dysfunction and depression in a subset of patients. Contemporary management of disorders of male orgasm and ejaculation. This procedure is usually done at the doctor's office. After a bit over a week I decreased the dose to 10mg before bedtime and none in the afternoon. Why not save the other half for your next dose? The only thing that makes sense is to push your androgen receptors and epigenetics the opposite way fin did.