. ", Mayo Clinic: High blood pressure (hypertension)., Panminerva Medica: "Pycnogenol improvements in asthma management. Traditionally, people might drink a brew made from pine bark -- rich in pycnogenol -- as a treatment. There havent been enough studies yet to change practice protocols for treating children. but is for informational and educational purposes alone. A 2015 review indicates that pine bark extract can be used to treat metabolic syndrome and related disorders such as obesity, diabetes, and high blood pressure. A popular variety is the pinus maritime or the maritime pine that grows exclusively along the coast of southwest France. Pycnogenol seems well-tolerated for use in adults for up to 6 months. Add to Cart. 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In the study, it reduced cold symptoms and complications, the number of lost working days, and the use of over-the-counter medications compared to those who did not supplement with the extract [60]. In those treated with Pycnogenol, the edema score was increased by 17.9% versus an increase of 58.3% in the control group. This can cause pain, especially in areas of the body that are used repeatedly, like your hands, fingers, and knees. People who use the supplement along with their traditional medication usually take smaller doses than those who only take the supplement. A study of 66 healthy adults found that Pycnogenol may reduce the number of leg cramps experienced [11]. The results of a 2013 animal study suggest that pine bark extract may help to reduce damage to nerve cells following a traumatic brain injury. Research into Pycnogenol has revealed some promising results in over 30 health conditions. Enzogenol also may reduce mental fatigue and sleep problems [82]. Pycnogenol (up to 200 mg/day) may improve asthma and reduce inflammatory asthma markers in the blood, leukotrienes, after 4 weeks, according to a randomized placebo-controlled trial of 26 asthma patients [14]. However, in all the above studies insulin levels did not change. Perimenopausal women who took pine bark extract for eight weeks noticed decreased cholesterol and triglyceride levels. Procyanidins are chain-like structures consisted of catechins similar to some found in green tea (the green tea catechins that do not have 'gallate' in their names). Pycnogenol is a natural plant extract originating from the bark of the maritime pine that grows along the coast of southwest France and is found to contain a unique combination of procyanidins . Known for its antioxidant properties, Pycnogenol offers a wide range of potential health benefits. View as: Grid List. In a smaller study of 58 people, pycnogenol reduced the inflammatory marker CRP [49, 50]. In patients with chronic venous insufficiency, the number of muscle cramps decreased from 6.3 to 2.6; in athletes from 8.6 to 2.4. Used early on, it may prevent eye damage and blindness from diabetes [34]. Another clinical trial of 76 people with allergic asthma also suggests that Pycnogenol may reduce IgE antibodies and asthma symptoms [18, 16]. WebMD does not provide medical advice, diagnosis or treatment. DOI: Scheff SW, et al. Pycnogenol (100 mg/day) may reduce hay fever symptoms, according to a clinical trial of 39 people. Twenty-one patients were given Pycnogenol at 150 mg daily and 18 patients received no treatment for a period of eight weeks. Interesting activities, new dishes in restaurants, specialty ingredients, explanations of some netizens questions, etc.Hu Xuan is even helping Fatty s company s tourism manager, managing with Vice President Du Meixin, such as arranging guests reasonably.By the way.Dad, I want to tell you something.I plan to invest in the hotels and entertainment centers in the . Patients were given 100 milligrams of Pycnogenol, a branded version of pine bark extract, for 12 weeks, with continued anti-diabetic treatment. Another one of its exemplary effects is helping manage blood pressure levels. Upset stomach. A total of 40 patients with retinopathy (damage to the retina part of the eye) from diabetes and other vascular causes were enrolled in one study. Studies on human subjects have reported few side effects - even . Pycnogenol acts as a sustained-release formulation. These benefits appeared to persist for some time even after stopping supplementation [72]. - Please read carefully and implement principles included in the Health Recovery Plan. 10 Ways to Control Blood Sugar without Medication, Pycnogenol (French Maritime Pine Bark Extract): 12 Benefits According to Studies, Reduces leaky blood vessels by making the wall proteins (collagen, elastin) more resistant to damage, Helps maintain high vitamin C and E blood levels for their antioxidant effects, Inhibits platelet aggregation like low-dose aspirin, Reduces hardening in the arteries by increasing nitric oxide production in blood vessels, leading to greater dilatation, Counteracts the damaging effects of ultraviolet radiation, Stimulates the immune system by boosting T and B cell functions, Protects brain cells from toxic chemicals. Pine bark extract offers some amazing benefits since its so high in powerful antioxidants. Since components of Pycnogenol can be modified during digestion and absorption as well as by the liver, diseases that affect the gut or liver may increase or decrease its effects [84]. Along with the rest of the crew, he developed symptoms of vitamin-C deficiency. We believe that the most accurate information is found directly in the scientific source. It also reduced the size of scars. In clinical research, doses up to about 300 mg/day have been used for up to one year without major safety concerns [33, 37]. All included participants had subclinical cognitive impairment, which looks like typical brain fog [22]. Pycnogenol (150 mg/day) reduced LDL and increased HDL cholesterol in a trial of 25 healthy people after 6 weeks [55]. In a study of 61 ADHD children, pycnogenol reduced hyperactivity, improved attention, and motorics after 1 month. Pycnogenol-treated subjects experienced an improvement in all menopausal symptoms. According to some researchers, Pycnogenol may lower blood pressure by relaxing blood vessels, reducing free radicals, and lowering inflammation. (4). While it may seem intimidating at first, counting macros is a common Erythritol is now one of the most popular natural zero-calorie sweeteners available. Pycnogenol treatment reduced the need for painkillers by 58% versus one percent in the placebo-treated group. Various brands of pycnogenol are available. Another 2006 study examined the effects of the antioxidant activity of pine bark extract on oxidative stress, which is thought to be one of the nongenetic factors contributing to ADHD. Children who took a pine bark extract supplement for one month had healthy antioxidant levels. Lets begin with asthma. Most anal fissures heal with home treatment after a few days or weeks. Studies have found that when taken along with an inhaler, Pycnogenol can reduce leukotrienes, helping to relieve lung inflammation and limit frequency of inhaler use., Many people develop osteoarthritis as they age. In long-haul flights, Pycnogenol could be an effective prevention for blood clots. Researchers suggest it may boost sustained attention, memory, executive functions, mood, and reduce oxidative stress [19]. Plus, it reduced total and LDL (bad) cholesterol. Additionally, the results showed that the extract has significant anti-pseudomonas activity, making it a potential natural remedy and possible preventive measure for infections. Typical doses range from 50 milligrams to 450 milligrams per day. (10), A 15-year Dutch study was published stating that 27,939 healthy female health professionals were given aspirin or a placebo for a period of time. Commonly called arthritis, osteoarthritis is caused when the cartilage on your joints begins to wear down. In a study of 20 postmenopausal women, 12 weeks of pycnogenol supplementation improved hydration and elasticity of the skin. In another trial, a combination supplement (Pycnogenol 60 mg/day, L-arginine 690 mg/day and aspartic acid 552 mg/day) improved erectile dysfunction and sexual satisfaction in men after 8 weeks. Results failed to show any efficacy of Pycnogenol or methylphenidate when compared to placebo. Pine bark extract provides many benefits to the skin, including reducing the signs of aging. 11 Skin elasticity increased, and skin fatigue decreased significantly in this study as well, further lowering the wrinkling risk. Erythritol: Is This Healthy Sweetener the Real Deal? In contrast, almost 20% of the participants on inhalers alone had to increase their dosage. But two months ago, erectile dysfunction health food with the help of the Divine Tool Alliance, the price of all materials related to the puppet mechanism was raised by 20 erectile dysfunction health food 30 , and the price of selling the puppet was reduced by 10. A study with four groups of 30 patients each were studied: (1) systemic Pycnogenol and local application; (2) local Pycnogenol only; (3) oral Pycnogenol and (4) medications only (control). In a double-blind, placebo-controlled, randomized, crossover study, 50 patients with erectile dysfunction (ED) were treated with either L-arginine plus Pycnogenol or placebo for a month. The U.S. Food and Drug Administration (FDA) does regulate dietary supplements; however, it treats them like foods rather than medications. 5) Inflammation and Allergies. A randomized, double-blind, placebo-controlled study of 60 patients aged six to 18 years old, was conducted over three months during which patients were randomly assigned to receive either Pycnogenol or placebo. 7. Instead, use plain water to wipe yourself and then dry your bottom afterward. Pine bark extract can help reduce muscle soreness and may help improve conditions relating to poor circulation, high blood pressure, osteoarthritis, diabetes, ADHD, female reproductive issues, skin, erectile dysfunction, eye disease and sports stamina. We don't yet know what the best dose to use is, but studies have used two 50 mg Pycnogenol capsules per day. Pycnogenol lotions applied postirradiation reduced this immunosuppression to 22% (0.05% Pycnogenol) and 13% (0.1% Pycnogenol). Joe Cohen flipped the script on conventional and alternative medicine and it worked. The usual recommended duration of treatment for topical application is 7 days for Pycnogenol cream and 6 weeks for Pycnogenol powder. This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. The study showed that many people who participated had a drop in their systolic blood pressure after taking Pycnogenol. One study suggests that Pycnogenol has no effect when given just 3 weeks beforehand, as it possibly requires a lag time to stabilize the immune response [17]. Vinpocetine is used to increase brain circulation, alertness, cognitive function, concentration, and memory, as well as to lower inflammation and oxidative stress.This article will explore vinpocetine's history, how it works, its potential benefits, and any possible safety issues . A 2004 animal study also found that applying a gel containing pine bark extract sped up the wound-healing process. Its likely that muscle recovery time improved as well due to the high antioxidants pine bark extract contains. Seems like it must be pretty amazing, but lets look closer. Researchers suggest that it may epigenetically turn off genes responsible for joint damage (ADAMTS) as well as reduce inflammation enzymes (MMP3) and cytokines (IL 1-beta) [47, 48]. Pine bark extract can be found in liquid, tablet or capsule form containing 85 percent to 90 percent OPCs. Chestnut seed extract did not do as well. If a blood clot blocks the normal blood flow, it is known as thrombosis. Several studies show how Pycnogenol helps block platelet formation and thus helps prevent thrombosis. Pycnogenol health benefits. According to some researchers, when you take Pycnogenol [8]: Research suggests that Pycnogenol may protect cells in the body against oxidative stress. So begins my look at the natural supplement, pycnogenol (French Maritime Pine Bark Extract)benefits. In a clinical trial of 116 women, Pycnogenol (60 mg/day) reduced menstrual pain and the need for additional painkillers, taken over 2 cycles. Grape seed extract may have heart-health benefits. Pycnogenol (pic-noj-en-all) is a natural plant extract originating from the bark of the maritime pine that grows along the coast of southwest France and is found to contain a unique combination of procyanidins, bioflavonoids and phenolic acids, which offer extensive natural health benefits. One way to add some extra flavor and nutrients to your day is by adding prune juice to your diet. The review found evidence that pine bark extract may: Similar to its neuroprotective benefits, the metabolic benefits of pine bark extract seem to be related to its antioxidant and anti-inflammatory properties. But what makes this miracle ingredient so amazing? Optimal doses of pycnogenol have not been set for any condition. Diindolylmethane, or DIM for short, is a plant indolea plant compound with health-promoting properties. 4. A deficiency can cause issues like anemia, stunted growth, heart problems and neural tube defects. For poor circulation: 45360 milligrams daily or 50100 milligrams three times daily. Forty patients were treated with either 600 mg chestnut seed extract a day or 360 mg Pycnogenol a day over a period of four weeks. Interactions. Pycnogenol French maritime pine bark extract's 4 basic properties. No side effects were noted, unlike its synthetic counterpart. Ana spent years working with patients who suffer from various mental health issues and chronic health problems. For asthma in children: 1 milligram per pound of body weight given in two divided doses. In a clinical trial of 92 people with tinnitus, or ringing in the ears, Pycnogenol (100-150 mg/day) helped reduce symptoms and improve blood flow in the ears after 4 weeks [80]. Pycnogenol improved symptoms, circulation, and reduced complications in 156 people with deep vein thrombosis (blot clots in deep leg veins) in a 12-month study. She loves communicating science and empowering people to achieve their optimal health. For children with ADHD, research suggests that symptoms start to return after about a month without taking maritime pine, so taking periodic breaks shouldnt make it any less effective. (2012). Pycnogenol is a patented formulation of Pine Bark Extract which is standardized to 65-75% Procyanidin compounds by weight. In a study of 50 overweight people, a combination product (Pycnogenol, Madeglucyl, and starches called Glucaffect) reduced weight, BMI, blood glucose, and HbA1C after 8 weeks [30]. However, it is also important to see beyond the pyncogenol marketing campaign and understand the possible dangers associated with this natural supplement. Pycnogenol is thought to be an antioxidant that helps protect cells from damage. The list goes on a bit further, as the OPCs in thisextract may inhibit lipid peroxidation, platelet aggregation, capillary permeability and fragility, and to affect enzyme systems, which basically means it may be a natural treatment for many serious health conditions, such as stroke and heart disease. Talk to your own doctor about Pycnogenol if youre interested in using it for your own health. But, as you know, going for the natural approach can make a huge difference in overall health. Research indicates that Pycnogenol provides an increase in endurance performance of trained athletes. Lower the risk of Alzheimer's disease. Note that the numbers in parentheses (1, 2, etc.)